Accurate spike sorting for multi-unit recordings
نویسندگان
چکیده
منابع مشابه
Cross-channel correlations in tetrode recordings: implications for spike-sorting
We are exploring new methods of spike detection to improve spike-sorting in tetrode recordings. Based on our observation that the four channels of the tetrode carry highly correlated signals, we propose the use of a hyperellipsoidal thresholding surface in the 4-dimensional space of the signal values to detect spikes. This surface is determined by the cross-channel covariance matrix and provide...
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We examine the problem of estimating the spike trains of multiple neurons from voltage traces recorded on one or more extracellular electrodes. Traditional spike-sorting methods rely on thresholding or clustering of recorded signals to identify spikes. While these methods can detect a large fraction of the spikes from a recording, they generally fail to identify synchronous or near-synchronous ...
متن کاملSorting Overlapping Spike Waveforms from Electrode and Tetrode Recordings
One of the outstanding problems in the sorting of neuronal spike trains is the resolution of overlapping spikes. Resolving these spikes can significantly improve a range of analyses, such as response variability, correlation, and latency. In this paper, we describe a partially automated method that is capable of resolving overlapping spikes. After constructing template waveforms for well-isolat...
متن کاملA Brief Look into Spike Sorting Methods
Spike sorting is a class of techniques used in the analysis of electrophysiological data. Studying the dynamics of neural activity via electrical recording relies on the ability to detect and sort neural spikes recorded from a number of neurons by the same electrode. This article reviews methods for detecting and classifying action potentials, a problem commonly referred to as spike sorting.
متن کاملSpike sorting
Figure 1. Extracellular recordings and spike sorting. (A) The extracellular activity of neurons is recorded with microwires inserted in the brain. The spikes of neurons close-by the electrode tip (in red and blue) can be separated via spike sorting; neurons further away (in dark grey) can be detected but not sorted, thus generating the multiunit activity; more distant neurons (in light gray) co...
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ژورنال
عنوان ژورنال: European Journal of Neuroscience
سال: 2010
ISSN: 0953-816X,1460-9568
DOI: 10.1111/j.1460-9568.2009.07068.x